The Role of the AT-Rich Interaction Domain 1A Gene (<i>ARID1A</i>) in Human Carcinogenesis

The switch/sucrose non-fermentable (SWI/SNF) (SWI/SNF) complex uses energy from ATP hydrolysis to mobilise nucleosomes on chromatin. Components of SWI/SNF are mutated in 20% of all human cancers, of which mutations in AT-rich binding domain protein 1A (<i>ARID1A</i>) are the most common....

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Bibliographic Details
Main Authors: Jing Jing Li, Cheok Soon Lee
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/15/1/5