Does toe clipping for genotyping interfere with later-in-life nociception in mice?

Abstract. Introduction:. Genetically modified mice are widely used in studies on human and animal physiology and pharmacology, including pain research. The experimental design usually includes comparisons of genetically modified mice with wild-type littermates, requiring biopsy material for genotypi...

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Bibliographic Details
Main Authors: Noémie Frezel, Gilles Kratzer, Philipp Verzar, Jérôme Bürki, Fabienne A. Weber, Hanns Ulrich Zeilhofer
Format: Article
Language:English
Published: Wolters Kluwer 2019-06-01
Series:PAIN Reports
Online Access:http://journals.lww.com/painrpts/fulltext/10.1097/PR9.0000000000000740