Undercarboxylated osteocalcin inhibits the early differentiation of osteoclast mediated by Gprc6a

Osteocalcin (OCN) was the most abundant noncollagen protein and considered as an endocrine factor. However, the functions of Undercarboxylated osteocalcin (ucOCN) on osteoclast and bone resorption are not well understood. In the present study, preosteoclast RAW264.7 cells and bone marrow mononuclear...

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Bibliographic Details
Main Authors: Hailong Wang, Jinqiao Li, Zihan Xu, Feng Wu, Hongyu Zhang, Chao Yang, Jian Chen, Bai Ding, Xiukun Sui, Zhifeng Guo, Yinghui Li, Zhongquan Dai
Format: Article
Language:English
Published: PeerJ Inc. 2021-03-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/10898.pdf