SERS-Based Assessment of MRD in Acute Promyelocytic Leukemia?

SERS-Based Assessment of MRD in Acute Promyelocytic Leukemia?

Acute promyelocytic leukemia (APL) is characterized by a unique chromosome translocation t(15;17)(q24;q21), which leads to the PML/RARA gene fusion formation. However, it is acknowledged that this rearrangement alone is not able to induce the whole leukemic phenotype. In addition, epigenetic process...

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Bibliographic Details
Main Authors: Cristina Turcas, Vlad Moisoiu, Andrei Stefancu, Ancuta Jurj, Stefania D. Iancu, Patric Teodorescu, Sergiu Pasca, Anca Bojan, Adrian Trifa, Sabina Iluta, Alina-Andreea Zimta, Bobe Petrushev, Mihnea Zdrenghea, Horia Bumbea, Daniel Coriu, Delia Dima, Nicolae Leopold, Ciprian Tomuleasa
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Oncology
Subjects:
DNA methylation
acute promyelocytic leukemia
measurable residual disease
disease monitoring
patient follow-up
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01024/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.01024/full

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