Caveolin-1 regulates OMV-induced macrophage pro-inflammatory activation and multiple Toll-like receptors

Caveolin-1 regulates OMV-induced macrophage pro-inflammatory activation and multiple Toll-like receptors

Macrophages (MФ), the primary cell of the innate immune system, serves as the first line of defense. During bacterial infection, Gram-negative (G-) bacteria release nanosized outer membrane vesicles (OMVs), facilitating the crosstalk between the microbe and the host. The underlying mechanisms by whi...

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Bibliographic Details
Main Authors: Ayyanar Sivanantham, Ward Alktaish, Selvakumar Murugeasan, Bin Gong, Heedoo Lee, Yang Jin
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Immunology
Subjects:
macrophage activation
inflammation
bacterial infection
OMV
bacteria
caveolin-1
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1044834/full

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