Angiotensin II modulates THP-1-like macrophage phenotype and inflammatory signatures via angiotensin II type 1 receptor

Angiotensin II modulates THP-1-like macrophage phenotype and inflammatory signatures via angiotensin II type 1 receptor

Angiotensin II (Ang II) is a major component of the renin–angiotensin or renin–angiotensin–aldosterone system, which is the main element found to be involved in cardiopathology. Recently, long-term metabolomics studies have linked high levels of angiotensin plasma to inflammatory conditions such as...

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Bibliographic Details
Main Authors: Tlili Barhoumi, Fatmah A. Mansour, Maroua Jalouli, Hassan S. Alamri, Rizwan Ali, Abdel Halim Harrath, Maha Aljumaa, Mohamed Boudjelal
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
angiotensin II
macrophages
ROS
inflammation
angiotensin II type 1 receptor (AT1R)
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2023.1129704/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2023.1129704/full

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