Role of Organic Cation Transporter 2 in Autophagy Induced by Platinum Derivatives

Role of Organic Cation Transporter 2 in Autophagy Induced by Platinum Derivatives

The human organic cation transporter 2 (hOCT2) mediates renal and neuronal cellular cisplatin and oxaliplatin uptake, and therefore plays a significant role in the development of side effects associated with these chemotherapeutic drugs. Autophagy is induced by cisplatin and oxaliplatin treatment an...

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Bibliographic Details
Main Authors: Sara Ahmed Eltayeb, Giuliano Ciarimboli, Katrin Beul, Giovana Seno Di Marco, Vivien Barz
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
transport
platinum derivatives
toxicity
autophagy
Online Access:https://www.mdpi.com/1422-0067/23/3/1090

Internet

https://www.mdpi.com/1422-0067/23/3/1090

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