SMC3 epigenetic silencing regulates Rab27a expression and drives pancreatic cancer progression
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is expected to soon surpass colorectal cancer as a leading cause of cancer mortality in both males and females in the US, only lagging behind lung cancer. The lethality of PDAC is driven by late diagnosis and inefficient therapies. The comp...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-08-01
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Series: | Journal of Translational Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12967-023-04448-1 |