Identification of novel imidazo[1,2-a]pyridine inhibitors targeting M. tuberculosis QcrB.

Identification of novel imidazo[1,2-a]pyridine inhibitors targeting M. tuberculosis QcrB.

Mycobacterium tuberculosis is a major human pathogen and the causative agent for the pulmonary disease, tuberculosis (TB). Current treatment programs to combat TB are under threat due to the emergence of multi-drug and extensively-drug resistant TB. Through the use of high throughput whole cell scre...

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Main Authors: Katherine A Abrahams, Jonathan A G Cox, Vickey L Spivey, Nicholas J Loman, Mark J Pallen, Chrystala Constantinidou, Raquel Fernández, Carlos Alemparte, Modesto J Remuiñán, David Barros, Lluis Ballell, Gurdyal S Besra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3534098?pdf=render

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http://europepmc.org/articles/PMC3534098?pdf=render

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