miRNA-218 Targets Lipin-1 and Glucose Transporter Type 4 Genes in 3T3-L1 Cells Treated With Lopinavir/Ritonavir

miRNA-218 Targets Lipin-1 and Glucose Transporter Type 4 Genes in 3T3-L1 Cells Treated With Lopinavir/Ritonavir

Background: Metabolic complications represent a common and serious problem associated with HIV infection and combined Antiretroviral Therapy (cART). Alterations in body fat distribution are associated with significantly increased risks of (i) metabolic derangements, (ii) cardiovascular pathologies,...

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Bibliographic Details
Main Authors: Elena Bresciani, Cecilia Saletti, Nicola Squillace, Laura Rizzi, Laura Molteni, Ramona Meanti, Robert J. Omeljaniuk, Giuseppe Biagini, Andrea Gori, Vittorio Locatelli, Antonio Torsello
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Pharmacology
Subjects:
HIV protease inhibitors
lipodystrophy
miRNA
adipocyte
insulin resistance
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00461/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00461/full

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