Excipient of paclitaxel induces metabolic dysregulation and unfolded protein response

Excipient of paclitaxel induces metabolic dysregulation and unfolded protein response

Summary: Taxane-based reagents, such as Taxol, Taxotere, and Abraxane, are popular anti-cancer drugs that can differ in their clinical efficacy. This difference is generally attributed to their active pharmaceutical ingredients. Here, we report a serendipitous discovery that Taxol induces metabolic...

Full description

Bibliographic Details
Main Authors: Qian Dai, Xiaolin Liu, Tao He, Chao Yang, Jinfeng Jiang, Yin Fang, Zhoukai Fu, Yuan Yuan, Shujun Bai, Tong Qiu, Rutie Yin, Ping Ding, Jie Chen, Qintong Li
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:iScience
Subjects:
Biological sciences
Molecular biology
Cell biology
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422101138X

Internet

http://www.sciencedirect.com/science/article/pii/S258900422101138X

Similar Items