What is the optimal dose of adipose-derived mesenchymal stem cells treatment for knee osteoarthritis? A conventional and network meta-analysis of randomized controlled trials

Abstract Background Despite increasing clinical investigations underscoring the efficacy and safety of adipose-derived mesenchymal stem cells (AD-MSCs) therapy in knee osteoarthritis (KOA), no article has recently reviewed the cell dosage. This study aimed to evaluate the efficacy and safety of vary...

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Bibliographic Details
Main Authors: Zongyuan Huang, Shuai Zhang, Mingde Cao, Zhujian Lin, Ling Kong, Xin Wu, Qianshi Guo, Yuxiang Ouyang, Yancheng Song
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13287-023-03475-5