Cancer-Associated Fibroblasts in Pancreatic Cancer: Should They Be Deleted or Reeducated?

Pancreatic ductal adenocarcinoma is characterized by an extensive stromal response called desmoplasia. Within the tumor stroma, cancer-associated fibroblasts (CAFs) are the primary cell type. CAFs have been shown to play a role in pancreatic cancer progression; they secrete growth factors, inflammat...

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Bibliographic Details
Main Authors: Chao Qu PhD, Qing Wang MD, Zhiqiang Meng PhD, Peng Wang PhD
Format: Article
Language:English
Published: SAGE Publishing 2018-12-01
Series:Integrative Cancer Therapies
Online Access:https://doi.org/10.1177/1534735418794884