Cancer-Associated Fibroblasts in Pancreatic Cancer: Should They Be Deleted or Reeducated?
Pancreatic ductal adenocarcinoma is characterized by an extensive stromal response called desmoplasia. Within the tumor stroma, cancer-associated fibroblasts (CAFs) are the primary cell type. CAFs have been shown to play a role in pancreatic cancer progression; they secrete growth factors, inflammat...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2018-12-01
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Series: | Integrative Cancer Therapies |
Online Access: | https://doi.org/10.1177/1534735418794884 |