Optimization and evaluation of a live virus SARS-CoV-2 neutralization assay.

Optimization and evaluation of a live virus SARS-CoV-2 neutralization assay.

Virus neutralization assays provide a means to quantitate functional antibody responses that block virus infection. These assays are instrumental in defining vaccine and therapeutic antibody potency, immune evasion by viral variants, and post-infection immunity. Here we describe the development, opt...

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Bibliographic Details
Main Authors: Anders Frische, Patrick Terrence Brooks, Mikkel Gybel-Brask, Susanne Gjørup Sækmose, Bitten Aagaard Jensen, Susan Mikkelsen, Mie Topholm Bruun, Lasse Boding, Charlotta Polacek Strandh, Charlotte Sværke Jørgensen, Karen Angeliki Krogfelt, Anders Fomsgaard, Ria Lassauniere
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0272298

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https://doi.org/10.1371/journal.pone.0272298

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