Massive expansion of multiple clones in the mouse hematopoietic system long after whole-body X-irradiation
Abstract Clonal hematopoiesis (CH) is prevalent in the elderly and associates with hematologic malignancy and cardiovascular disease. Although the risk of developing these diseases increases with radiation doses in atomic-bomb survivors, the causal relationship between radiation exposure and CH is u...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-10-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-21621-6 |