Utilization of nicking properties of CRISPR-Cas12a effector for genome editing

Utilization of nicking properties of CRISPR-Cas12a effector for genome editing

Abstract The CRISPR-Cas nickase system for genome editing has attracted considerable attention owing to its safety, efficiency, and versatility. Although alternative effectors to Cas9 have the potential to expand the scope of genome editing, their application has not been optimized. Herein, we used...

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Bibliographic Details
Main Authors: Chan Hyoung Kim, Wi-jae Lee, Yeounsun Oh, Youngjeon Lee, Hyomin K. Lee, Jung Bae Seong, Kyung-Seob Lim, Sang Je Park, Jae-Won Huh, Young-Hyun Kim, Kyoung Mi Kim, Junho K. Hur, Seung Hwan Lee
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-53648-2

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https://doi.org/10.1038/s41598-024-53648-2

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