The lipid-lowering drug fenofibrate combined with si-HOTAIR can effectively inhibit the proliferation of gliomas

Abstract Background Fenofibrate is a fibric acid derivative known to have a lipid-lowering effect. Although fenofibrate-induced peroxisome proliferator-activated receptor alpha (PPARα) transcription activation has been shown to play an important role in the malignant progression of gliomas, the unde...

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Bibliographic Details
Main Authors: Wei Zhu, Hongyang Zhao, Fenfen Xu, Bin Huang, Xiaojing Dai, Jikui Sun, Alphonce M. K. Nyalali, Kailiang Zhang, Shilei Ni
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-021-08417-z