Conjugated Bile Acids Promote Lymphangiogenesis by Modulation of the Reactive Oxygen Species–p90RSK–Vascular Endothelial Growth Factor Receptor 3 Pathway

Conjugated Bile Acids Promote Lymphangiogenesis by Modulation of the Reactive Oxygen Species–p90RSK–Vascular Endothelial Growth Factor Receptor 3 Pathway

Conjugated bile acids (BA) are significantly elevated in several liver pathologies and in the metastatic lymph node (LN). However, the effects of BAs on pathological lymphangiogenesis remains unknown. The current study explores the effects of BAs on lymphangiogenesis. BA levels were elevated in the...

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Bibliographic Details
Main Authors: Priyanka Banerjee, Subhashree Kumaravel, Sukanya Roy, Niyanshi Gaddam, Johnny Odeh, Kayla J. Bayless, Shannon Glaser, Sanjukta Chakraborty
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Cells
Subjects:
bile acids
lymphatic endothelial cells
lymphangiogenesis
oxidative stress
growth factor signaling
Online Access:https://www.mdpi.com/2073-4409/12/4/526

Internet

https://www.mdpi.com/2073-4409/12/4/526

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