Single‐cell and spatial omics unravel the spatiotemporal biology of tumour border invasion and haematogenous metastasis

Abstract Solid tumours exhibit a well‐defined architecture, comprising a differentiated core and a dynamic border that interfaces with the surrounding tissue. This border, characterised by distinct cellular morphology and molecular composition, serves as a critical determinant of the tumour's i...

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Bibliographic Details
Main Authors: Xifu Cheng, Yuke Cao, Xiangyi Liu, Yuanheng Li, Qing Li, Dian Gao, Qiongfang Yu
Format: Article
Language:English
Published: Wiley 2024-10-01
Series:Clinical and Translational Medicine
Subjects:
Online Access:https://doi.org/10.1002/ctm2.70036