Components of a Fanconi-like pathway control Pso2-independent DNA interstrand crosslink repair in yeast.
Fanconi anemia (FA) is a devastating genetic disease, associated with genomic instability and defects in DNA interstrand cross-link (ICL) repair. The FA repair pathway is not thought to be conserved in budding yeast, and although the yeast Mph1 helicase is a putative homolog of human FANCM, yeast ce...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
|
Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC3415447?pdf=render |