Inactivation of the SGS1 and EXO1 Genes Synergistically Stimulates Plasmid Integration in Yeast

Different procedures used for targeted genetic manipulations are based on homologous recombination between chromosomal and exogenous DNA. A double-strand break (DSB) present on the plasmid molecule stimulates and directs plasmid integration to the homologous sequence in the yeast genome and we wonde...

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Bibliographic Details
Main Authors: Anamarija Štafa, Ivan-Krešimir Svetec, Zoran Zgaga
Format: Article
Language:English
Published: University of Zagreb Faculty of Food Technology and Biotechnology 2005-01-01
Series:Food Technology and Biotechnology
Subjects:
Online Access:http://hrcak.srce.hr/file/162751