Chrysomycin A Regulates Proliferation and Apoptosis of Neuroglioma Cells via the Akt/GSK-3β Signaling Pathway In Vivo and In Vitro

Chrysomycin A Regulates Proliferation and Apoptosis of Neuroglioma Cells via the Akt/GSK-3β Signaling Pathway In Vivo and In Vitro

Glioblastoma (GBM) is a major type of primary brain tumor without ideal prognosis and it is therefore necessary to develop a novel compound possessing therapeutic effects. Chrysomycin A (Chr-A) has been reported to inhibit the proliferation, migration and invasion of U251 and U87-MG cells through th...

Full description

Bibliographic Details
Main Authors: Dong-Ni Liu, Man Liu, Shan-Shan Zhang, Yu-Fu Shang, Wen-Fang Zhang, Fu-Hang Song, Hua-Wei Zhang, Guan-Hua Du, Yue-Hua Wang
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Marine Drugs
Subjects:
Chrysomycin A
xenograft mouse model
glioblastoma
apoptosis
Online Access:https://www.mdpi.com/1660-3397/21/6/329

Internet

https://www.mdpi.com/1660-3397/21/6/329

Similar Items