Detection of Core2 β-1,6-N-Acetylglucosaminyltransferase in Post-Digital Rectal Examination Urine Is a Reliable Indicator for Extracapsular Extension of Prostate Cancer.

To identify appropriate candidates for aggressive treatment such as radical prostatectomy or radiation therapy of localized prostate cancer (PCa), novel predictive biomarkers of PCa aggressiveness are essential. Core2 β-1,6-N-acetylglucosaminyltransferase-1 (GCNT1) is a key enzyme that forms core 2-...

Full description

Bibliographic Details
Main Authors: Yuta Kojima, Tohru Yoneyama, Shingo Hatakeyama, Jotaro Mikami, Tendo Sato, Kazuyuki Mori, Yasuhiro Hashimoto, Takuya Koie, Chikara Ohyama, Minoru Fukuda, Yuki Tobisawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4577128?pdf=render