Single-cell dissection, hdWGCNA and deep learning reveal the role of oxidatively stressed plasma cells in ulcerative colitis

Single-cell dissection, hdWGCNA and deep learning reveal the role of oxidatively stressed plasma cells in ulcerative colitis

Ulcerative colitis (UC) develops as a result of complex interactions between various cell types in the mucosal microenvironment. In this study, we aim to elucidate the pathogenesis of ulcerative colitis at the single-cell level and unveil its clinical significance. Using single-cell RNA sequencing a...

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Bibliographic Details
Main Authors: Mo Shaocong, Shen Xin, Huang Baoxiang, Wang Yulin, Lin Lingxi, Chen Qiuming, Weng Meilin, Sugasawa Takehito, Gu Wenchao, Tsushima Yoshito, Nakajima Takahito
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2023-10-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
single-cell
hdWGCNA
deep learning
plasma cell
oxidative stress
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2023237

Internet

https://www.sciengine.com/doi/10.3724/abbs.2023237

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