Vinpocetine Protects Against Cerebral Ischemia-Reperfusion Injury by Targeting Astrocytic Connexin43 via the PI3K/AKT Signaling Pathway

Vinpocetine Protects Against Cerebral Ischemia-Reperfusion Injury by Targeting Astrocytic Connexin43 via the PI3K/AKT Signaling Pathway

Vinpocetine (Vinp) is known for its neuroprotective properties. However, the protective mechanism of Vinp against cerebral ischemia/reperfusion (I/R) injury should be further explored. This study was designed to investigate the neuroprotective effects of Vinp against oxygen-glucose deprivation/reoxy...

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Bibliographic Details
Main Authors: Mingming Zhao, Shuai Hou, Liangshu Feng, Pingping Shen, Di Nan, Yunhai Zhang, Famin Wang, Di Ma, Jiachun Feng
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Neuroscience
Subjects:
stroke
cerebral ischemia/reperfusion
oxygen-glucose deprivation/reoxygenation
vinpocetine
astrocyte
connexin 43
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00223/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2020.00223/full

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