Comparison of the Immunogenic Properties of Lactiplantibacillus plantarum Carrying the Mycobacterial Ag85B-ESAT-6 Antigen at Various Cellular Localizations

Comparison of the Immunogenic Properties of Lactiplantibacillus plantarum Carrying the Mycobacterial Ag85B-ESAT-6 Antigen at Various Cellular Localizations

The bacille Calmette-Guèrin (BCG) vaccine has been used for a century; nonetheless, tuberculosis (TB) remains one of the deadliest diseases in the world. Thus, new approaches to developing a new, more efficient vaccine are desirable. Mucosal vaccines are of particular interest, considering that Myco...

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Bibliographic Details
Main Authors: Kamilla Wiull, Preben Boysen, Katarzyna Kuczkowska, Lars Fredrik Moen, Harald Carlsen, Vincent G. H. Eijsink, Geir Mathiesen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Microbiology
Subjects:
mucosal vaccine platform
Lactiplantibacillus plantarum
delivery vector
tuberculosis
lactic acid bacteria
surface display
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.900922/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.900922/full

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