Gut environment-induced intraepithelial autoreactive CD4+ T cells suppress central nervous system autoimmunity via LAG-3

Experimental autoimmune encephalomyelitis (EAE) involves inflammatory cell infiltration into the central nervous system (CNS) and models the human disease multiple sclerosis. Here the authors show that transferred CD4+ gut intraepithelial lymphocytes can migrate into the CNS and inhibit inflammation...

詳細記述

書誌詳細
主要な著者: Atsushi Kadowaki, Sachiko Miyake, Ryoko Saga, Asako Chiba, Hideki Mochizuki, Takashi Yamamura
フォーマット: 論文
言語:English
出版事項: Nature Portfolio 2016-05-01
シリーズ:Nature Communications
オンライン・アクセス:https://doi.org/10.1038/ncomms11639