Pannexin 1 sustains the electrophysiological responsiveness of retinal ganglion cells

Pannexin 1 sustains the electrophysiological responsiveness of retinal ganglion cells

Abstract Pannexin 1 (Panx1) forms ATP-permeable membrane channels that play a key role in purinergic signaling in the nervous system in both normal and pathological conditions. In the retina, particularly high levels of Panx1 are found in retinal ganglion cells (RGCs), but the normal physiological f...

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Bibliographic Details
Main Authors: Galina Dvoriantchikova, Alexey Pronin, Sarah Kurtenbach, Abduqodir Toychiev, Tsung-Han Chou, Christopher W. Yee, Breanne Prindeville, Junior Tayou, Vittorio Porciatti, Botir T. Sagdullaev, Vladlen Z. Slepak, Valery I. Shestopalov
Format: Article
Language:English
Published: Nature Portfolio 2018-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-23894-2

Internet

https://doi.org/10.1038/s41598-018-23894-2

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