TCF19 promotes cell proliferation and tumor formation in lung cancer by activating the Raf/MEK/ERK signaling pathway

TCF19 promotes cell proliferation and tumor formation in lung cancer by activating the Raf/MEK/ERK signaling pathway

Objective: This study aimed to investigate TCF19′s role in lung cancer development, specifically its involvement in the RAF/MEK/ERK signaling pathway. Methods: Lung cancer tissue analysis revealed significant TCF19 overexpression. In vitro experiments using A549 and Hop62 cells with TCF19 overexpres...

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Bibliographic Details
Main Authors: Yahui Tian, Shaowei Xin, Zitong Wan, Honghong Dong, Lu Liu, Zhenzhen Fan, Tian Li, Fujun Peng, Yanlu Xiong, Yong Han
Format: Article
Language:English
Published: Elsevier 2024-07-01
Series:Translational Oncology
Subjects:
TCF19
Cell cycle
Raf/MEK/ERK pathway
Lung cancer
Tumor gene
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523324001050

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http://www.sciencedirect.com/science/article/pii/S1936523324001050

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