Efficacy of a food supplement based on S-adenosyl methionine and probiotic strains in subjects with subthreshold depression and mild-to-moderate depression: A monocentric, randomized, cross-over, double-blind, placebo-controlled clinical trial

Efficacy of a food supplement based on S-adenosyl methionine and probiotic strains in subjects with subthreshold depression and mild-to-moderate depression: A monocentric, randomized, cross-over, double-blind, placebo-controlled clinical trial

Depression is one of the most serious chronic psychiatric disorders affecting people worldwide. Subthreshold depression (SD) is a form of subclinical depression with increased risk of major depressive disorder (MDD). Patients diagnosed with SD may not be eligible for antidepressant drugs and, partic...

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Bibliographic Details
Main Authors: Hammad Ullah, Alessandro Di Minno, Cristina Esposito, Hesham R. El-Seedi, Shaden A.M. Khalifa, Alessandra Baldi, Agostino Greco, Salvatore Santonastaso, Valeria Cioffi, Raffaele Sperandeo, Roberto Sacchi, Maria Daglia
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Mild-to-moderate depression
Food supplement
Probiotics
S-adenosylmethionine
Subthreshold depression
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222013191

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http://www.sciencedirect.com/science/article/pii/S0753332222013191

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