The silencing of NREP aggravates OA cartilage damage through the TGF-β1/Smad2/3 pathway in chondrocytes

The silencing of NREP aggravates OA cartilage damage through the TGF-β1/Smad2/3 pathway in chondrocytes

Background: Osteoarthritis (OA) is a common chronic degenerative joint disease. Due to the limited understanding of its complex pathological mechanism, there is currently no effective treatment that can alleviate or even reverse cartilage damage associated with OA. With improvement in public databas...

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Bibliographic Details
Main Authors: Yang Liu, Mengrou Liu, Chengming Zhang, Xiaoke Li, Siyu Zheng, Le Wen, Peidong Liu, Pengcui Li, Ziquan Yang
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Journal of Orthopaedic Translation
Subjects:
Articular cartilage
Bioinformatics
NREP
Osteoarthritis
TGF-β1 /Smad2/3 pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X23000931

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http://www.sciencedirect.com/science/article/pii/S2214031X23000931

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