Eupalinolide B inhibits hepatic carcinoma by inducing ferroptosis and ROS-ER-JNK pathway

Eupalinolide B inhibits hepatic carcinoma by inducing ferroptosis and ROS-ER-JNK pathway

Primary hepatic carcinoma is a common malignant tumor. The classic molecular targeted drug sorafenib is costly and is only effective for some patients. Therefore, it is of great clinical significance to search for new molecular targeted drugs. Eupalinolide B (EB) from Eupatorium lindleyanum DC. is u...

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Bibliographic Details
Main Authors: Zhang Yonghui, Zhang Haoyang, Mu Jinage, Han Meiyue, Cao Zhihao, Dong Feng, Wang Tingting, Pan Lian, Luo Wujing, Li Jiaxin, Liu Huan, Jin Lishan, Ding Wenxuan, Wei Yong, Deng Xuesong, Liu Dan, He Xiuzhen, Pang Yi, Mu Xiao, Wu Zhongjun, Chen Dilong
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2022-07-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
Eupalinolide B
hepatic carcinoma
ferroptosis
HO-1
ER stress
JNK
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2022082

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https://www.sciengine.com/doi/10.3724/abbs.2022082

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