Use of a pulmosphere model to evaluate drug antifibrotic responses in interstitial lung diseases

Abstract Background Interstitial lung diseases (ILD) encompass a heterogenous group of diffuse parenchymal lung disorders characterized by variable degrees of inflammation and fibrosis. Pretherapeutic clinical testing models for such diseases can serve as a platform to test and develop effective the...

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Bibliographic Details
Main Authors: Kevin G. Dsouza, Ranu Surolia, Tejaswini Kulkarni, Fu Jun Li, Pooja Singh, Huaxiu Zeng, Crystal Stephens, Abhishek Kumar, Zheng Wang, Veena B. Antony
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Respiratory Research
Online Access:https://doi.org/10.1186/s12931-023-02404-7