Inflammatory dendritic cells restrain CD11b+CD4+ CTLs via CD200R in human NSCLC

Summary: CD4+ cytotoxic T lymphocytes (CD4+ CTLs) are suggested to play a crucial role in inflammatory diseases, including cancer, but their characteristics in human non-small cell lung cancer (NSCLC) remain unknown. Here, using the cell surface marker CD11b, we identify CD11b+CD4+ CTLs as a cytotox...

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Bibliographic Details
Main Authors: Mingjie Lin, Di Chen, Zheyu Shao, Qinyuan Liu, Zhixing Hao, Zhongwei Xin, Yongyuan Chen, Wenxuan Wu, Xiaoke Chen, Teng He, Dang Wu, Pin Wu
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Cell Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724000950