Regulatory T-cell mediated suppression of conventional T-cells and dendritic cells by different cAMP intracellular pathways.

Regulatory T-cell mediated suppression of conventional T-cells and dendritic cells by different cAMP intracellular pathways.

Regulatory T-cells (Tregs) mediate their suppressive action by acting directly on conventional T-cells (Tcons) or dendritic cells (DCs). One mechanism of Treg suppression is the increase of cyclic adenosine 3’,5’-monophosphate (cAMP) levels in target cells. Tregs utilize cAMP to control Tcon respons...

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Bibliographic Details
Main Authors: Cesar M Rueda, Courtney M Jackson, Claire A Chougnet
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-06-01
Series:Frontiers in Immunology
Subjects:
Suppression
T cells
Dentritic cells
cyclic adenosine monophosphate
Tregs; T regulatory Cells
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00216/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00216/full

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