Murine in utero exposure to simulated complex urban air pollution disturbs offspring gut maturation and microbiota during intestinal suckling-to-weaning transition in a sex-dependent manner

Murine in utero exposure to simulated complex urban air pollution disturbs offspring gut maturation and microbiota during intestinal suckling-to-weaning transition in a sex-dependent manner

Abstract Background Emerging data indicate that prenatal exposure to air pollution may lead to higher susceptibility to several non-communicable diseases. Limited research has been conducted due to difficulties in modelling realistic air pollution exposure. In this study, pregnant mice were exposed...

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Bibliographic Details
Main Authors: Eva Guilloteau, Patrice Coll, Zhuyi Lu, Madjid Djouina, Mathieu Cazaunau, Christophe Waxin, Antonin Bergé, Ségolène Caboche, Aline Gratien, Elie Al Marj, David Hot, Laurent Dubuquoy, David Launay, Cécile Vignal, Sophie Lanone, Mathilde Body-Malapel
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Particle and Fibre Toxicology
Subjects:
Air pollution
Gestational exposure
Intestinal development
Suckling-to-weaning transition
Microbiota
Maturation
Online Access:https://doi.org/10.1186/s12989-022-00481-y

Internet

https://doi.org/10.1186/s12989-022-00481-y

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