Melanoma Suppressor Functions of the Carcinoma Oncogene FOXQ1

Melanoma Suppressor Functions of the Carcinoma Oncogene FOXQ1

Lineage-specific regulation of tumor progression by the same transcription factor is understudied. We find that levels of the FOXQ1 transcription factor, an oncogene in carcinomas, are decreased during melanoma progression. Moreover, in contrast to carcinomas, FOXQ1 suppresses epithelial-to-mesenchy...

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Bibliographic Details
Main Authors: Archis Bagati, Anna Bianchi-Smiraglia, Sudha Moparthy, Kateryna Kolesnikova, Emily E. Fink, Brittany C. Lipchick, Masha Kolesnikova, Peter Jowdy, Anthony Polechetti, Amin Mahpour, Jason Ross, Joseph A. Wawrzyniak, Dong Hyun Yun, Gyorgy Paragh, Nadezhda I. Kozlova, Albert E. Berman, Jianmin Wang, Song Liu, Michael J. Nemeth, Mikhail A. Nikiforov
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Cell Reports
Subjects:
melanoma
carcinoma
FOXQ1
N-cadherin
β-catenin
epithelial-to-mesenchymal transition
invasion
metastasis
differentiation
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717311828

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http://www.sciencedirect.com/science/article/pii/S2211124717311828

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