Phosphorylation Status of GluN2B-Ser1303 Under Glutamate-induced Excitotoxicity in Primary Cortical Neurons: An In Vitro Study

Background: Glutamate, an excitatory neurotransmitter, plays a pivotal role in cellular phenomena in neurons, like synaptic plasticity and excitotoxicity. As the major glutamate receptors, N-methyl-D-aspartate receptors (NMDARs) undergo phosphorylation at Ser1303 on the GluN2B subunit upon glutamate...

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Bibliographic Details
Main Author: Ramya R Prabhu
Format: Article
Language:English
Published: Guilan University of Medical Sciences 2023-10-01
Series:Caspian Journal of Neurological Sciences
Subjects:
Online Access:http://cjns.gums.ac.ir/article-1-668-en.pdf