Noninvasive monitoring of bilirubin photoisomer excretion during phototherapy

Abstract Lumirubin is the most prevalently excreted hydrophilic bilirubin photoisomer in phototherapy for neonatal jaundice caused by excess hydrophobic unconjugated bilirubin (ZZ-bilirubin). We developed a simple method to estimate the amount of lumirubin by monitoring the reverse photoisomerizatio...

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Bibliographic Details
Main Authors: Yumiko Uchida, Yukihiro Takahashi, Yukihiro Morimoto, Peter Greimel, Asako Tosaki, Akiko Kumagai, Toshiya Nishikubo, Atsushi Miyawaki
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-16180-9