Theory of optimal balance predicts and explains the amplitude and decay time of synaptic inhibition

Inhibition and excitation are counterbalanced at synapses, but the conditions that constitute optimal balance are not known. Here the authors show through modelling that the properties of synaptic inhibition are fine-tuned to maintain an optimal balance in which peak excitation reaches precisely to...

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Bibliographic Details
Main Authors: Jaekyung K. Kim, Christopher D. Fiorillo
Format: Article
Language:English
Published: Nature Portfolio 2017-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms14566