Improving astaxanthin production in Escherichia coli by co-utilizing CrtZ enzymes with different substrate preference

Abstract Background The bifunctional enzyme β-carotene hydroxylase (CrtZ) catalyzes the hydroxylation of carotenoid β-ionone rings at the 3, 3’ position regardless of the presence of keto group at 4, 4’ position, which is an important step in the synthesis of astaxanthin. The level and substrate pre...

Full description

Bibliographic Details
Main Authors: Meng Zhang, Zhongkuo Gong, Jinlei Tang, Fuping Lu, QingYan Li, XueLi Zhang
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Microbial Cell Factories
Subjects:
Online Access:https://doi.org/10.1186/s12934-022-01798-1