Nebulized Mycobacterium vaccae protects against asthma by attenuating the imbalance of IRF4/IRF8 expression in dendritic cells

Nebulized Mycobacterium vaccae protects against asthma by attenuating the imbalance of IRF4/IRF8 expression in dendritic cells

Objective: To assess the effects of nebulized inhaled Mycobacterium vaccae on allergic airway inflammation, airway hyperresponsiveness, and Th1/Th2 cell imbalance in mice with ovalbumin (OVA)-induced asthma. Methods: Mice received OVA sensitization and challenge for establishment of the asthmatic mo...

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Bibliographic Details
Main Authors: Qi-Xiang Sun, Si-Yue Xu, Lao-Dong Li, Huan Xiao, Qian-Nan Zhang, Chao-Qian Li
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
mycobacterium vaccae; asthma; nebulization; irf4; irf8; tlr4
Online Access:http://www.apjtb.org/article.asp?issn=2221-1691;year=2022;volume=12;issue=12;spage=520;epage=529;aulast=Sun

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http://www.apjtb.org/article.asp?issn=2221-1691;year=2022;volume=12;issue=12;spage=520;epage=529;aulast=Sun

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