Penicillin kills Chlamydia following the fusion of bacteria with lysosomes and prevents genital inflammatory lesions in C. muridarum-infected mice.

The obligate intracellular bacterium Chlamydia exists as two distinct forms. Elementary bodies (EBs) are infectious and extra-cellular, whereas reticulate bodies (RBs) replicate within a specialized intracellular compartment termed an 'inclusion'. Alternative persistent intra-cellular form...

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Bibliographic Details
Main Authors: Maud Dumoux, Sylvain M Le Gall, Mohamed Habbeddine, Christiane Delarbre, Richard D Hayward, Colette Kanellopoulos-Langevin, Philippe Verbeke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3871543?pdf=render