Active constituent of Polygala tenuifolia attenuates cognitive deficits by rescuing hippocampal neurogenesis in APP/PS1 transgenic mice

Abstract Background Alzheimer’s disease (AD) is the most common dementia worldwide, and there is still no satisfactory drug or therapeutic strategy. Polygala tenuifolia is a traditional Chinese medicine with multiple neuroprotective effects. In present study, we investigated the effects of three act...

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Main Authors: Xiao-feng Wang, Hong-he Xiao, Yu-tong Wu, Liang Kong, Ji-cong Chen, Jing-xian Yang, Xiao-le Hu
格式: 文件
语言:English
出版: BMC 2021-10-01
丛编:BMC Complementary Medicine and Therapies
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在线阅读:https://doi.org/10.1186/s12906-021-03437-5