Sex differences in Alzheimer’s disease: plasma MMP-9 and markers of disease severity

Sex differences in Alzheimer’s disease: plasma MMP-9 and markers of disease severity

Abstract Background Studies have reported higher plasma matrix metalloproteinase-9 (MMP-9) levels in mild cognitive impairment (MCI) and Alzheimer’s disease (AD). Despite evidence that MMP-9 activity and its influence on AD pathophysiology may be modulated by sex hormones, sex differences in the ass...

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Bibliographic Details
Main Authors: Amaryllis A. Tsiknia, Erin E. Sundermann, Emilie T. Reas, Steven D. Edland, James B. Brewer, Douglas Galasko, Sarah J. Banks, for the Alzheimer’s Disease Neuroimaging Initiative
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Alzheimer’s Research & Therapy
Subjects:
Matrix metalloproteinase-9
Alzheimer’s disease
Mild cognitive impairment
Fluid biomarkers
Sex differences
Cognitive decline
Online Access:https://doi.org/10.1186/s13195-022-01106-4

Internet

https://doi.org/10.1186/s13195-022-01106-4

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