Pre-40S ribosome biogenesis factor Tsr1 is an inactive structural mimic of translational GTPases

Pre-40S ribosome biogenesis factor Tsr1 is an inactive structural mimic of translational GTPases

Tsr1 is an essential ribosome biogenesis factor that has known similarity to GTPases. Here, the authors report the Tsr1 crystal structure and show that it is similar to GTPases but that active site residues are not conserved; modelling of the structure into the pre-40S maps allows inferences on ribo...

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Bibliographic Details
Main Authors: Urszula M. McCaughan, Uma Jayachandran, Vadim Shchepachev, Zhuo Angel Chen, Juri Rappsilber, David Tollervey, Atlanta G. Cook
Format: Article
Language:English
Published: Nature Portfolio 2016-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11789

Internet

https://doi.org/10.1038/ncomms11789

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