Splanchnic sympathetic nerve denervation improves bacterial clearance and clinical recovery in established ovine Gram-negative bacteremia

Splanchnic sympathetic nerve denervation improves bacterial clearance and clinical recovery in established ovine Gram-negative bacteremia

Abstract Background The autonomic nervous system can modulate the innate immune responses to bacterial infections via the splanchnic sympathetic nerves. Here, we aimed to determine the effects of bilateral splanchnic sympathetic nerve denervation on blood pressure, plasma cytokines, blood bacterial...

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Bibliographic Details
Main Authors: Rachel M. Peiris, Clive N. May, Lindsea C. Booth, Robin M. McAllen, Michael J. McKinley, Sally Hood, Davide Martelli, Rinaldo Bellomo, Yugeesh R. Lankadeva
Format: Article
Language:English
Published: SpringerOpen 2023-08-01
Series:Intensive Care Medicine Experimental
Subjects:
Bacteremia
Sepsis
Splanchnic sympathetic nerves
Cytokines
Inflammation
Online Access:https://doi.org/10.1186/s40635-023-00530-6

Internet

https://doi.org/10.1186/s40635-023-00530-6

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