Association of PIK3CA mutation with outcomes in HER2-positive breast cancer treated with anti-HER2 therapy: A meta-analysis and bioinformatic analysis of TCGA‑BRCA data

Association of PIK3CA mutation with outcomes in HER2-positive breast cancer treated with anti-HER2 therapy: A meta-analysis and bioinformatic analysis of TCGA‑BRCA data

Background: This study aimed to comprehensively explore the clinical significance of PIK3CA mutation in human epidermal growth factor receptor 2 (HER2)-positive breast cancer treated with anti-HER2 therapy. Methods: We systematically searched PubMed, Embase, and the Cochrane databases for eligible s...

Full description

Bibliographic Details
Main Authors: Haizhu Chen, Xingbin Hu, Daquan Wang, Ying Wang, Yunfang Yu, Herui Yao
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Translational Oncology
Subjects:
Breast cancer
HER2-positive
Anti-HER2 therapy
PIK3CA mutation
Predictive
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523323001249

Internet

http://www.sciencedirect.com/science/article/pii/S1936523323001249

Similar Items