Female bias in Rhox6 and 9 regulation by the histone demethylase KDM6A.
The Rhox cluster on the mouse X chromosome contains reproduction-related homeobox genes expressed in a sexually dimorphic manner. We report that two members of the Rhox cluster, Rhox6 and 9, are regulated by de-methylation of histone H3 at lysine 27 by KDM6A, a histone demethylase with female-biased...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2013-05-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC3642083?pdf=render |