Comparative Fitness of a Parent Leishmania donovani Clinical Isolate and Its Experimentally Derived Paromomycin-Resistant Strain.

Paromomycin has recently been introduced for the treatment of visceral leishmaniasis and emergence of drug resistance can only be appropriately judged upon its long term routine use in the field. Understanding alterations in parasite behavior linked to paromomycin-resistance may be essential to asse...

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Bibliographic Details
Main Authors: Sarah Hendrickx, Annelies Leemans, Annelies Mondelaers, Suman Rijal, Basudha Khanal, Jean-Claude Dujardin, Peter Delputte, Paul Cos, Louis Maes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4607421?pdf=render